HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Houde, J. F. Articles by Merzenich, M. M. Search for Related Content PubMed PubMed Citation Articles by Houde, J. F. Articles by Merzenich, M. M.

Modulation of the Auditory Cortex during Speech: An MEG Study

University of California, San Francisco

Kensuke Sekihara

Tokyo Metropolitan Institute of Technology

Michael M. Merzenich

University of California, San Francisco

Several behavioral and brain imaging studies have demonstrated a significant interaction between speech perception and speech production. In this study, auditory cortical responses to speech were examined during self-production and feedback alteration. Magnetic field recordings were obtained from both hemispheres in subjects who spoke while hearing controlled acoustic versions of their speech feedback via earphones. These responses were compared to recordings made while subjects listened to a tape playback of their production. The amplitude of tape playback was adjusted to match the amplitude of self-produced speech. Recordings of evoked responses to both self-produced and tape-recorded speech were obtained free of movement-related artifacts. Responses to self-produced speech were weaker than were responses to tape-recorded speech. Responses to tones were also weaker during speech production, when compared with responses to tones recorded in the presence of speech from tape playback. However, responses evoked by gated noise stimuli did not differ for recordings made during self-produced speech versus recordings made during tape-recorded speech playback. These data suggest that during speech production, the auditory cortex (1) attenuates its sensitivity and (2) modulates its activity as a function of the expected acoustic feedback.

This article has been cited by other articles:

				J. T. Sakata and M. S. Brainard Online Contributions of Auditory Feedback to Neural Activity in Avian Song Control Circuitry J. Neurosci., October 29, 2008; 28(44): 11378 - 11390. [Abstract] [Full Text] [PDF]

				N. S. Dhanjal, L. Handunnetthi, M. C. Patel, and R. J. S. Wise Perceptual Systems Controlling Speech Production J. Neurosci., October 1, 2008; 28(40): 9969 - 9975. [Abstract] [Full Text] [PDF]

				V. L. Towle, H.-A. Yoon, M. Castelle, J. C. Edgar, N. M. Biassou, D. M. Frim, J.-P. Spire, and M. H. Kohrman ECoG gamma activity during a language task: differentiating expressive and receptive speech areas Brain, August 1, 2008; 131(8): 2013 - 2027. [Abstract] [Full Text] [PDF]

				T. H. Heinks-Maldonado, D. H. Mathalon, J. F. Houde, M. Gray, W. O. Faustman, and J. M. Ford Relationship of Imprecise Corollary Discharge in Schizophrenia to Auditory Hallucinations Arch Gen Psychiatry, March 1, 2007; 64(3): 286 - 296. [Abstract] [Full Text] [PDF]

				S. J. Eliades and X. Wang Dynamics of Auditory-Vocal Interaction in Monkey Auditory Cortex Cereb Cortex, October 1, 2005; 15(10): 1510 - 1523. [Abstract] [Full Text] [PDF]

				M. H. Martikainen, K.-i. Kaneko, and R. Hari Suppressed Responses to Self-triggered Sounds in the Human Auditory Cortex Cereb Cortex, March 1, 2005; 15(3): 299 - 302. [Abstract] [Full Text] [PDF]

				S. J. Eliades and X. Wang Sensory-Motor Interaction in the Primate Auditory Cortex During Self-Initiated Vocalizations J Neurophysiol, April 1, 2003; 89(4): 2194 - 2207. [Abstract] [Full Text] [PDF]