| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Stanford University
Massachusetts Institute of Technology
Stanford University
The ability to cognitively regulate emotional responses to aversive events is important for mental and physical health. Little is known, however, about neural bases of the cognitive control of emotion. The present study employed functional magnetic resonance imaging to examine the neural systems used to reappraise highly negative scenes in unemotional terms. Reappraisal of highly negative scenes reduced subjective experience of negative affect. Neural correlates of reappraisal were increased activation of the lateral and medial prefrontal regions and decreased activation of the amygdala and medial orbito-frontal cortex. These findings support the hypothesis that prefrontal cortex is involved in constructing reappraisal strategies that can modulate activity in multiple emotion-processing systems.
This article has been cited by other articles:
|
|
 |
|
  M. Koenigs, E. D. Huey, M. Calamia, V. Raymont, D. Tranel, and J. Grafman Distinct Regions of Prefrontal Cortex Mediate Resistance and Vulnerability to Depression J. Neurosci., November 19, 2008; 28(47): 12341 - 12348. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J Bell Propranolol, post-traumatic stress disorder and narrative identity J. Med. Ethics, November 1, 2008; 34(11): e23 - e23. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. S. Dichter, C. Bellion, M. Casp, and A. Belger Impaired Modulation of Attention and Emotion in Schizophrenia Schizophr Bull, October 8, 2008; (2008) sbn118v1. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Herbert, T. Ethofer, S. Anders, M. Junghofer, D. Wildgruber, W. Grodd, and J. Kissler Amygdala activation during reading of emotional adjectives--an advantage for pleasant content Soc Cogn Affect Neurosci, September 27, 2008; (2008) nsn027v1. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. A. Miller, R. L. Collins, and T. A. Kent Language and the Modulation of Impulsive Aggression J Neuropsychiatry Clin Neurosci, August 1, 2008; 20(3): 261 - 273. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. M. Muller, S. K. Andersen, and A. Keil Time Course of Competition for Visual Processing Resources between Emotional Pictures and Foreground Task Cereb Cortex, August 1, 2008; 18(8): 1892 - 1899. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Foti and G. Hajcak Deconstructing reappraisal: descriptions preceding arousing pictures modulate the subsequent neural response. J. Cogn. Neurosci., June 1, 2008; 20(6): 977 - 988. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. M. LECLERC and E. A. KENSINGER Age-related differences in medial prefrontal activation in response to emotional images Cogn Affect Behav Neurosci, June 1, 2008; 8(2): 153 - 164. [Abstract] [PDF]
|
|
|
|
|
|
T. Egner, A. Etkin, S. Gale, and J. Hirsch Dissociable Neural Systems Resolve Conflict from Emotional versus Nonemotional Distracters Cereb Cortex, June 1, 2008; 18(6): 1475 - 1484. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Lerner, A. Bagic, T. Hanakawa, E. A. Boudreau, F. Pagan, Z. Mari, W. Bara-Jimenez, M. Aksu, S. Sato, D. L. Murphy, et al. Involvement of Insula and Cingulate Cortices in Control and Suppression of Natural Urges Cereb Cortex, May 9, 2008; (2008) bhn074v1. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. McRae, K. N. Ochsner, I. B. Mauss, J. J. D. Gabrieli, and J. J. Gross Gender Differences in Emotion Regulation: An fMRI Study of Cognitive Reappraisal Group Processes Intergroup Relations, April 1, 2008; 11(2): 143 - 162. [Abstract] [PDF]
|
|
|
|
|
|
J. F. Dovidio, A. R. Pearson, and P. Orr Social Psychology and Neuroscience: Strange Bedfellows or a Healthy Marriage? Group Processes Intergroup Relations, April 1, 2008; 11(2): 247 - 263. [Abstract] [PDF]
|
|
|
|
 |
|
 S. Whittle, M. B. H. Yap, M. Yucel, A. Fornito, J. G. Simmons, A. Barrett, L. Sheeber, and N. B. Allen Prefrontal and amygdala volumes are related to adolescents' affective behaviors during parent-adolescent interactions PNAS, March 4, 2008; 105(9): 3652 - 3657. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. D. Lane Neural Substrates of Implicit and Explicit Emotional Processes: A Unifying Framework for Psychosomatic Medicine Psychosom Med, February 1, 2008; 70(2): 214 - 231. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. M. Goghari and A. W. MacDonald III Effects of varying the experimental design of a cognitive control paradigm on behavioral and functional imaging outcome measures. J. Cogn. Neurosci., January 1, 2008; 20(1): 20 - 35. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. L. Keightley, K. S. Chiew, G. Winocur, and C. L. Grady Age-related differences in brain activity underlying identification of emotional expressions in faces Soc Cogn Affect Neurosci, December 1, 2007; 2(4): 292 - 302. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Sheppes and N. Meiran Better Late Than Never? On the Dynamics of Online Regulation of Sadness Using Distraction and Cognitive Reappraisal Pers Soc Psychol Bull, November 1, 2007; 33(11): 1518 - 1532. [Abstract] [PDF]
|
|
|
|
|
|
A. V. Rauch, P. Ohrmann, J. Bauer, H. Kugel, A. Engelien, V. Arolt, W. Heindel, and T. Suslow Cognitive Coping Style Modulates Neural Responses to Emotional Faces in Healthy Humans: A 3-T fMRI Study Cereb Cortex, November 1, 2007; 17(11): 2526 - 2535. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Johnstone, C. M. van Reekum, H. L. Urry, N. H. Kalin, and R. J. Davidson Failure to Regulate: Counterproductive Recruitment of Top-Down Prefrontal-Subcortical Circuitry in Major Depression J. Neurosci., August 15, 2007; 27(33): 8877 - 8884. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. E. Depue, T. Curran, and M. T. Banich Prefrontal Regions Orchestrate Suppression of Emotional Memories via a Two-Phase Process Science, July 13, 2007; 317(5835): 215 - 219. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Brefczynski-Lewis, A. Lutz, H. S. Schaefer, D. B. Levinson, and R. J. Davidson Neural correlates of attentional expertise in long-term meditation practitioners PNAS, July 3, 2007; 104(27): 11483 - 11488. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. D. Creswell, B. M. Way, N. I. Eisenberger, and M. D. Lieberman Neural Correlates of Dispositional Mindfulness During Affect Labeling Psychosom Med, July 1, 2007; 69(6): 560 - 565. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Kross, T. Egner, K. Ochsner, J. Hirsch, and G. Downey Neural dynamics of rejection sensitivity. J. Cogn. Neurosci., June 1, 2007; 19(6): 945 - 956. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. H. Kim and S. Hamann Neural correlates of positive and negative emotion regulation. J. Cogn. Neurosci., May 1, 2007; 19(5): 776 - 798. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Jokela, L. Keltikangas-Jarvinen, M. Kivimaki, S. Puttonen, M. Elovainio, R. Rontu, and T. Lehtimaki Serotonin Receptor 2A Gene and the Influence of Childhood Maternal Nurturance on Adulthood Depressive Symptoms Arch Gen Psychiatry, March 1, 2007; 64(3): 356 - 360. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Beaucousin, A. Lacheret, M.-R. Turbelin, M. Morel, B. Mazoyer, and N. Tzourio-Mazoyer FMRI Study of Emotional Speech Comprehension Cereb Cortex, February 1, 2007; 17(2): 339 - 352. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Koenigs and D. Tranel Irrational Economic Decision-Making after Ventromedial Prefrontal Damage: Evidence from the Ultimatum Game J. Neurosci., January 24, 2007; 27(4): 951 - 956. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Lamm, C. D. Batson, and J. Decety The Neural Substrate of Human Empathy: Effects of Perspective-taking and Cognitive Appraisal. J. Cogn. Neurosci., January 1, 2007; 19(1): 42 - 58. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Calandreau, P. Trifilieff, N. Mons, L. Costes, M. Marien, A. Marighetto, J. Micheau, R. Jaffard, and A. Desmedt Extracellular Hippocampal Acetylcholine Level Controls Amygdala Function and Promotes Adaptive Conditioned Emotional Response J. Neurosci., December 27, 2006; 26(52): 13556 - 13566. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. M. Drabant, A. R. Hariri, A. Meyer-Lindenberg, K. E. Munoz, V. S. Mattay, B. S. Kolachana, M. F. Egan, and D. R. Weinberger Catechol O-methyltransferase Val158Met Genotype and Neural Mechanisms Related to Affective Arousal and Regulation Arch Gen Psychiatry, December 1, 2006; 63(12): 1396 - 1406. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Westen, P. S. Blagov, K. Harenski, C. Kilts, and S. Hamann Neural bases of motivated reasoning: an FMRI study of emotional constraints on partisan political judgment in the 2004 u.s. Presidential election. J. Cogn. Neurosci., November 1, 2006; 18(11): 1947 - 1958. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Kalisch, K. Wiech, K. Herrmann, and R. J. Dolan Neural Correlates of Self-distraction from Anxiety and a Process Model of Cognitive Emotion Regulation. J. Cogn. Neurosci., August 1, 2006; 18(8): 1266 - 1276. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. L. Urry, C. M. van Reekum, T. Johnstone, N. H. Kalin, M. E. Thurow, H. S. Schaefer, C. A. Jackson, C. J. Frye, L. L. Greischar, A. L. Alexander, et al. Amygdala and ventromedial prefrontal cortex are inversely coupled during regulation of negative affect and predict the diurnal pattern of cortisol secretion among older adults. J. Neurosci., April 19, 2006; 26(16): 4415 - 4425. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Kruger, M. Alda, L. T. Young, K. Goldapple, S. Parikh, and H. S. Mayberg Risk and Resilience Markers in Bipolar Disorder: Brain Responses to Emotional Challenge in Bipolar Patients and Their Healthy Siblings Am J Psychiatry, February 1, 2006; 163(2): 257 - 264. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. L. Phan, J. C. Britton, S. F. Taylor, L. M. Fig, and I. Liberzon Corticolimbic Blood Flow During Nontraumatic Emotional Processing in Posttraumatic Stress Disorder Arch Gen Psychiatry, February 1, 2006; 63(2): 184 - 192. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. de Gelder, J. S. Morris, and R. J. Dolan Unconscious fear influences emotional awareness of faces and voices PNAS, December 20, 2005; 102(51): 18682 - 18687. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Benedetti, H. S. Mayberg, T. D. Wager, C. S. Stohler, and J.-K. Zubieta Neurobiological Mechanisms of the Placebo Effect J. Neurosci., November 9, 2005; 25(45): 10390 - 10402. [Full Text] [PDF]
|
|
|
|
 |
|
 H. J. Rosen, S. C. Allison, G. F. Schauer, M. L. Gorno-Tempini, M. W. Weiner, and B. L. Miller Neuroanatomical correlates of behavioural disorders in dementia Brain, November 1, 2005; 128(11): 2612 - 2625. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. M Barch The Relationships Among Cognition, Motivation, and Emotion in Schizophrenia: How Much and How Little We Know Schizophr Bull, October 1, 2005; 31(4): 875 - 881. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Kalisch, K. Wiech, H. D. Critchley, B. Seymour, J. P. O'Doherty, D. A. Oakley, P. Allen, and R. J. Dolan Anxiety Reduction through Detachment: Subjective, Physiological, and Neural Effects J. Cogn. Neurosci., June 1, 2005; 17(6): 874 - 883. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Mathews, J. Yiend, and A. D. Lawrence Individual Differences in the Modulation of Fear-Related Brain Activation by Attentional Control J. Cogn. Neurosci., December 1, 2004; 16(10): 1683 - 1694. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Kim, L. H. Somerville, T. Johnstone, S. Polis, A. L. Alexander, L. M. Shin, and P. J. Whalen Contextual Modulation of Amygdala Responsivity to Surprised Faces J. Cogn. Neurosci., December 1, 2004; 16(10): 1730 - 1745. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. N. Ochsner, K. Knierim, D. H. Ludlow, J. Hanelin, T. Ramachandran, G. Glover, and S. C. Mackey Reflecting upon Feelings: An fMRI Study of Neural Systems Supporting the Attribution of Emotion to Self and Other J. Cogn. Neurosci., December 1, 2004; 16(10): 1746 - 1772. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. D. Woolley, M. L. Gorno-Tempini, K. Werner, K. P. Rankin, P. Ekman, R. W. Levenson, and B. L. Miller The autonomic and behavioral profile of emotional dysregulation Neurology, November 9, 2004; 63(9): 1740 - 1743. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. M. McClure, D. I. Laibson, G. Loewenstein, and J. D. Cohen Separate Neural Systems Value Immediate and Delayed Monetary Rewards Science, October 15, 2004; 306(5695): 503 - 507. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Petrovic, K. Carlsson, K. M. Petersson, P. Hansson, and M. Ingvar Context-dependent Deactivation of the Amygdala during Pain J. Cogn. Neurosci., August 1, 2004; 16(7): 1289 - 1301. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Decety and P. L. Jackson The Functional Architecture of Human Empathy Behav Cogn Neurosci Rev, June 1, 2004; 3(2): 71 - 100. [Abstract] [PDF]
|
|
|
|
|
|
M. C. Anderson, K. N. Ochsner, B. Kuhl, J. Cooper, E. Robertson, S. W. Gabrieli, G. H. Glover, and J. D. E. Gabrieli Neural Systems Underlying the Suppression of Unwanted Memories Science, January 9, 2004; 303(5655): 232 - 235. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Goldapple, Z. Segal, C. Garson, M. Lau, P. Bieling, S. Kennedy, and H. Mayberg Modulation of Cortical-Limbic Pathways in Major Depression: Treatment-Specific Effects of Cognitive Behavior Therapy Arch Gen Psychiatry, January 1, 2004; 61(1): 34 - 41. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Rosenkranz, H. Moore, and A. A. Grace The Prefrontal Cortex Regulates Lateral Amygdala Neuronal Plasticity and Responses to Previously Conditioned Stimuli J. Neurosci., December 3, 2003; 23(35): 11054 - 11064. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. K. Anderson, K. Christoff, D. Panitz, E. De Rosa, and J. D. E. Gabrieli Neural Correlates of the Automatic Processing of Threat Facial Signals J. Neurosci., July 2, 2003; 23(13): 5627 - 5633. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| NEURAL COMPUTATION | J COGNITIVE NEUROSCIENCE | MIT PRESS JOURNALS |
